Disney Television Animation's Emmy Award-winning animated series Phineas and Ferb pays homage to ABC's hit series Lost with a special episode featuring story by Lost co-creator and writer Damon Lindelof and guest starring Lost fan-favorite Terry O'Quinn (John Locke), premiering Monday, September 29 (7:30 p.m., ET/PT) on Disney XD.

The episode, titled "Lost in Danville," also guest stars Jane Kaczmarek (Malcolm in the Middle) and Rob Morrow (Numb3rs).

A mysterious locked capsule falls into Phineas and Ferb's back yard and they struggle to open it, only to discover they have unleashed something they cannot control. Meanwhile, Perry learns that Dr. Doofenshmirtz has been abducted and tracks him to Seattle where another evil scientist Professor Mystery has his own sinister plan.

Terry O'Quinn voices Professor Mystery, with Jane Kaczmarek and Rob Morrow as capsule inhabitants Denise and Bernie.

Source: Disney XD